%0 Journal Article
%T Maternal and fetal outcomes of primary immune thrombocytopenia during pregnancy: A retrospective study
%A C McLintock
%A KS Gilmore
%J Obstetric Medicine
%@ 1753-4968
%D 2018
%R 10.1177/1753495X17727408
%X We reviewed outcomes of 52 pregnancies in 45 women with immune thrombocytopenic purpura who delivered at Auckland Hospital with an antenatal platelet count of <100£¿¡Á£¿109/L. Primary outcomes were maternal platelet count at delivery and treatment response. Secondary outcomes included post-partum haemorrhage (PPH). Most women had thrombocytopenia at delivery. Treatment with prednisone was given in 14 (27%) pregnancies with responses considered safe for delivery in 11 pregnancies (79%). Women in eight pregnancies also received intravenous immunoglobulin; in five pregnancies (63%) a platelet response acceptable for delivery was achieved. Seventeen pregnancies (33%) were complicated by a PPH ¡Ý500£¿mL. Ten pregnancies (19%) were complicated by a PPH ¡Ý1000£¿mL. PPH was reported in all women with a platelet count <50£¿¡Á£¿109/L at delivery. There were no antenatal bleeding complications but PPH was common among women with platelet counts <50£¿¡Á£¿109/L at the time of birth
%K Platelets
%K immune thrombocytopenic purpura
%K prednisone
%K intravenous immunoglobulin
%K pregnancy
%K post-partum haemorrhage
%U https://journals.sagepub.com/doi/full/10.1177/1753495X17727408