%0 Journal Article
%T Perinatal management of hepatitis B virus: Clinical implementation of updated Australasian management guidelines
%A Gillian Wood
%A Hannah Bergin
%A Lisa Hui
%A Susan P Walker
%J Obstetric Medicine
%@ 1753-4968
%D 2018
%R 10.1177/1753495X17731990
%X To evaluate the implementation of the 2013 Royal Australian and New Zealand College of Obstetricians and Gynaecologists ¡®Management of Hepatitis B in Pregnancy¡¯ guideline. Retrospective cohort study of the clinical management and obstetric outcomes among hepatitis B virus-positive women in a single tertiary maternity hospital. Women with viral load >200,000£¿IU/ml were referred to a specialised clinic for consideration of tenofovir disoproxil fumarate therapy to reduce mother to child transmission. A total of 11,496 women gave birth during the study period, of which 101 (0.9%) women were hepatitis B virus positive. Viral load was measured in 99 (98%) of 101 hepatitis B virus-positive women; 30 (30%) had a viral load >200,000£¿IU/ml. Twenty-six women accepted tenofovir disoproxil fumarate; of these, 23 had a successful virological response (viral load <200,000£¿IU/ml before delivery). Adherence to updated management guidelines and patient acceptance of tenofovir disoproxil fumarate in our Australian population were high when provided in the context of a dedicated perinatal service
%K Hepatology
%K perinatal medicine
%K infectious diseases
%K gastroenterology
%K drugs (medication)
%U https://journals.sagepub.com/doi/full/10.1177/1753495X17731990