%0 Journal Article
%T Cytotoxic Sesquiterpenoids From Soft Soral Capnella imbricata
%A Charles Santhanaraju Vairappan
%A Chin-Soon Phan
%A Takahiro Ishii
%A Takashi Kamada
%A Toshiyuki Hamada
%J Natural Product Communications
%@ 1555-9475
%D 2019
%R 10.1177/1934578X19857494
%X A new sesquiterpene, capgermacrene H (1) was isolated together with 7 other compounds, capgermacrenes A-G (2-8), from a population of soft coral Capnella imbricata collected from Mantanani Island, Sabah, Malaysia. The structure of this metabolite was elucidated based on spectroscopic data such as nuclear magnetic resonance and high-resolution electrospray ionization mass spectrometry. Capgermacrene A (2) showed potent cytotoxicity against adult T-cell leukemia, S1T cells at half-maximal inhibitory concentration of 0.79 ¦Ìg/mL
%K Capnella
%K soft coral
%K sesquiterpene
%K capgermacrene H
%K cytotoxicity
%K adult T-cell leukemia
%U https://journals.sagepub.com/doi/full/10.1177/1934578X19857494