%0 Journal Article
%T Remission of chronic headache: Rates, potential predictors and the role of medication, follow
%A Mark Obermann
%A Sara Schramm
%A Susanne Moebus
%A Verena Henning
%A Zaza Katsarava
%J Cephalalgia
%@ 1468-2982
%D 2018
%R 10.1177/0333102417699180
%X To estimate remission rates of chronic headache (CH), focusing on potential predictors of headache remission and medication. We used data from the longitudinal population-based German Headache Consortium (GHC) Study (nˋ=ˋ9,944, 18每65 years). Validated questionnaires were used at baseline (t0, 2003每2007, response rate: 55.2%), first follow-up after 1.87ˋ㊣ˋ0.39 years (t1, 37.2%) and second follow-up after 3.26ˋ㊣ˋ0.60 years (t2, 38.8%) to assess headache type and frequency, use of analgesics and anti-migraine drugs, medication overuse, education, BMI, smoking and alcohol consumption. CH was defined asˋ≡ˋ15 headache days/month at t0 over three months. Outcomes were: CH remission (<15 headache days/month at both follow-ups), CH persistence (≡ 15 headache days/month at both follow-ups); all others were considered as partially remitted. To estimate predictors of remission, univariate and multiple logistic regression were calculated. At baseline, 255 (2.6%) participants were identified with CH. Of these, 158 (62.0%) participants responded at both follow-ups. Remission was observed in 58.2% of participants, partial remission in 17.7% and persistence in 24.1%. Remission was associated with female sex (adjusted odds ratio: 3.10, 95% confidence interval: 1.06每9.08) and no medication overuse (4.16, 1.45每11.94) compared to participants with persistent CH; participants with higher headache frequency at t0 were less likely to remit (0.90, 0.84每0.97). Medication, age, education, BMI, smoking and drinking showed no effects on remission. Similar results were observed for partial remission. The majority of CH participants remitted from CH. Female sex, no overuse of pain medication and lower headache frequency were associated with remission
%K Migraine
%K tension type headache
%K cohort study
%K medication overuse
%K headache frequency
%K longitudinal population-based study
%U https://journals.sagepub.com/doi/full/10.1177/0333102417699180