%0 Journal Article
%T Klinefelterand#8217;s Syndrome with a Cutaneous Manifestation of Lower Limb Ulceration
%A Ashwini Babu
%A Jacintha Martis
%A John Joseph S Martis
%A Sudeep D
%J Open Journal of Immunology
%D 2015
%R 10.4172/2155-9554.1000278
%X Klinefelter¡¯s syndrome (KS) is considered the most common type of male hypogonadism. The majority (80-90%) of patients are seen to have 47 XXY karyotype. Leg ulceration has been described as a complication of Klinefelter¡¯s syndrome. A young 21 year old male presented with a non-healing ulcer of the lower extremity of three years duration. Doppler studies and autoimmune workup was negative. However, clinical and further laboratory findings were consistent with Klinefelter¡¯s Syndrome. This case report highlights the importance of screening for chromosomal abnormalities besides evaluating for peripheral vascular disease, venous stasis and diabetes mellitus especially in a young male patient with chronic leg ulceration.
%K Jacintha Martis
%K Ashwini Babu
%K Sudeep D and John Joseph S Martis
%K Klinefelter¡¯s syndrome
%K Chronic leg ulceration
%U https://www.longdom.org/abstract/klinefelter8217s-syndrome-with-a-cutaneous-manifestation-of-lower-limb-ulceration-11951.html