%0 Journal Article %T Extracorporeal Shock Wave Therapy in the Treatment of Non-Healing Diabetic Ulcer: A Pilot Study %A Alireza Firooz %A Hournaz Hasanzadeh %A Nessa Aghazadeh %A Zeinab Variji %J Open Journal of Immunology %D 2015 %R 10.4172/2155-9554.10000289 %X 15-20% of all diabetic patients develop a foot ulcer. Diabetic ulcer is the major cause of non-traumatic lower extremity amputation. Extracorporeal shock wave therapy (ESWT) has emerged as a promising therapy in the field of wound healing. In this study, Five patients with diabetic foot (mean age of 58.2 ¡À 19.63 years, mean ulcer duration: 1.6 years), received ESWT in 6-8 weekly sessions, at a flux density of 0.25 mJ/mm2, delivered as 500 shocks at wound margin and 1000 shocks distal to the wound. All patients had evidence of peripheral vascular disease and neuropathy before treatment. A significant reduction in ulcer surface area was observed in four patients (mean reduction: 1.21 ¡À 0.82 cm2, p value=0.03). All patients showed improvement in the ankle brachial index and monofilament test after treatment. In sum, ESWT may be a promising adjunct in the treatment of chronic, non-healing diabetic ulcers. %K Zeinab Variji %K Nessa Aghazadeh %K Hournaz Hasanzadeh and Alireza Firooz %K Diabetes complication %K Ulcer %K High-energy shockwave %U https://www.longdom.org/abstract/extracorporeal-shock-wave-therapy-in-the-treatment-of-nonhealing-diabetic-ulcer-a-pilot-study-11962.html