%0 Journal Article
%T Activity of Serum and Salivary a-Amylase in Habitual Adult Tobacco
Consumers
%A Leila Badirou
%A Moutawakilou  Gomina
%A Simon Ayeleroun  Akpona
%J Open Journal of Immunology
%D 2013
%R 10.4172/2161-1009.1000140
%X Introduction: Tobacco consumption alters many biological parameters, as well as ¦Á-amylase activity. This research work aims to study the activity of serum and salivary alpha-amylase in habitual adult tobacco consumers. Methods: We carried out a cross-sectional descriptive and analytical study on 234 adults (54 smokers, 60 snuffers, 60 chewers and 60 tobacco non-consumers). Serum and salivary alpha-amylase was measured using kinetic enzymatic method. ANOVA, and Kruskal-Wallis test were used to compare averages according to cases. Linear regression enabled to establish relationships between duration of consumption, quantity of tobacco consumption, as well as serum and salivary ¦Á-amylase activity. Results and conclusion: The mean activity of serum (UI/L) and salivary (104 UI/L) alpha-amylase was respectively 110.53 ¡À 73.35 and 17.34 ¡À 17 for smokers, 109.69 ¡À 58.20 and 9.90 ¡À 9.44 for snuffers, 92.63 ¡À 48.84 and 5.61 ¡À 5.38 for chewers and 120.14 ¡À 71.99 and 8.73 ¡À 6.14 for tobacco non-consumers. A significant difference was observed as regards salivary alpha-amylase between smokers and chewers (p<0.001), and between snuffers and chewers (p=0.002). The mean activity of serum and salivary alpha-amylase was substantially higher in tobacco non-consumers than in chewers (p=0.01 and 0.02, respectively). Correlation was lower and significant in chewers between mean activity, salivary alpha-amylase and duration of tobacco consumption (r=0.35; inclination p=0.006). Serum and salivary alpha-amylase activity varies according to tobacco consumption mode. Subsequent studies are required to specify the mechanisms put at stake
%K Tobacco consumption alters many biological parameters
%K as well as ¦Á-amylase activity. This research work aims to study the activity of serum and salivary alpha-amylase in habitual adult tobacco consumers.
Methods: We carried out a cross-sectional descriptive and analytical study on 234 adults (54 smokers
%K 60 snuffers
%K 60 chewers and 60 tobacco non-consumers). Serum and salivary alpha-amylase was measured using kinetic enzymatic method. ANOVA
%K and Kruskal-Wallis test were used to compare averages according to cases. Linear regression enabled to establish relationships between duration of consumption
%K quantity of tobacco consumption
%K as well as serum and salivary ¦Á-amylase activity.
Results and conclusion: The mean activity of serum (UI/L) and salivary (104 UI/L) alpha-amylase was respectively 110.53 ¡À 73.35 and 17.34 ¡À 17 for smokers
%K 109.69 ¡À 58.20 and 9.90 ¡À 9.44 for snuffers
%K 92.63 ¡À 48.84 and 5.61 ¡À 5.38 for chewers and 120.14 ¡À 71.99 and 8.73 ¡À 6.14 for tobacco non-consumers. A significant difference was observed as regards salivary alpha-amylase between smokers and chewers (p<0.001)
%K and between snuffers and chewers (p=0.002). The mean activity of serum and salivary alpha-amylase was substantially higher in tobacco non-consumers than in chewers (p=0.01 and 0.02
%K respectively). Correlation was lower and significant in chewers between mean activity
%K salivary alpha-amylase and duration of tobacco consumption (r=0.35
%K inclination p=0.006). Serum and salivary alpha-amylase activity varies according to tobacco consumption mode. Subsequent studies are required to specify the mechanisms put at stake.
%U https://www.longdom.org/abstract/activity-of-serum-and-salivary-aamylase-in-habitual-adult-tobaccoconsumers-33363.html