%0 Journal Article %T SMAC Mimetics: Promising Therapeutic Agents in Cancer and other Diseases %A Laurence Dubrez %J Open Journal of Immunology %D 2018 %R 10.4172/2167-0501.1000244 %X Smac mimetics are a very promising new class of anticancer agents demonstrating an acceptable safety profile and efficacy in some preclinical models of cancers when used as a single agent or in combination with conventional or nonconventional therapies. Future preclinical and clinical trials could enlarge their spectral of action in inflammatory, fibrotic and infectious diseases. %K Laurence Dubrez %K Smac mimetics %K Nonconventional therapies %K Apoptosis %K Inflammasome %U https://www.longdom.org/abstract/smac-mimetics-promising-therapeutic-agents-in-cancer-and-other-diseases-17334.html