%0 Journal Article %T Medical ICU Insulin Infusion Protocols %A Abbas E. Kitabchi %A MD %A Amado X. Freire %A MD %A Angel Temponi %A MD %A Bruce W. Bode %A MD %A Christopher A. Newton %A MD %A Dawn Smiley %A MD %A Frankie Stentz %A PhD %A Guillermo E. Umpierrez %A MD %A Limin Peng %A PhD %A Patrick Mulligan %A BA %A Paul C. Davidson %A MD %A R. Dennis Steed %A MD %A Sol Jacobs %A MD %J Journal of Hospital Medicine %D 2010 %R 10.1002/jhm.816 %X AbstractPURPOSE:To compare the safety and efficacy of continuous insulin infusion (CII) via a computer©\guided and a standard paper form protocol in a medical intensive care unit (ICU).METHODS:Multicenter randomized trial of 153 ICU patients randomized to CII using the Glucommander (n = 77) or a standard paper protocol (n = 76). Both protocols used glulisine insulin and targeted blood glucose (BG) between 80 mg/dL and 120 mg/dL.RESULTS:The Glucommander resulted in a lower mean BG value (103 ¡À 8.8 mg/dL vs. 117 ¡À 16.5 mg/dL, P < 0.001) and in a shorter time to reach BG target (4.8 ¡À 2.8 vs.7.8 hours ¡À 9.1 hours, P < 0.01), and once at target resulted in a higher percentage of BG readings within target (71.0 ¡À 17.0% vs. 51.3 ¡À 19.7%, P < 0.001) than the standard protocol. Mean insulin infusion rate in the Glucommander was similar to the standard protocol (P = 0.12). The percentages of patients with ¡Ý1 episode of B %U https://www.journalofhospitalmedicine.com/jhospmed/article/127216/medical-icu-insulin-infusion-protocols