%0 Journal Article %T Giant juvenile fibroadenoma: a systematic review with diagnostic and treatment recommendations %A Eduardo D. Rodriguez %A Elizabeth D. Feldman %A Jason M. Weissler %A Ketan M. Patel %A Marisa Pulcrano %A Maurice Y. Nahabedian %A Michael Sosin %J SCIE-indexed Journal %D 2015 %X Fibroadenomas are the most common type of breast tumors diagnosed in young women. Fibroadenomas found in children and adolescents are termed juvenile fibroadenomas (1). A juvenile fibroadenoma is considered ¡°giant¡± if it is greater than 5 cm, 500 grams, or replaces at least 80% of the breast (1). Giant juvenile fibroadenomas are less common than fibroadenomas and comprise 1-8% of breast lesions in the adolescent population (1,2). Management of juvenile fibroadenomas includes surgical resection or observation since complete tumor regression may occur in 10-59% of lesions (1,3). These benign tumors have a propensity for rapid growth resulting in discomfort, self-consciousness, and anxiety (4,5). This is known to result in unpleasant interactions with their peers and has a considerable impact on these patients¡¯ psychological and emotional state (4). Other conditions of the breast tissue may be mistaken for fibroadenomas including physiologic hypertrophy, phyllodes tumor, and inflammatory processes such as a breast abscess (6) %U http://gs.amegroups.com/article/view/6851/7731