%0 Journal Article
%T Exosomes as ˇ°translationalˇ± cancer promoter organelles
%A Isabella Panfoli
%J SCIE-indexed Journal
%D 2016
%R 10.21037/9015
%X The term Exosome has come into use to define nano-vesicles contained in multivesicular endosomes (MVE), secreted by fusion of MVE with the plasma membrane (1-3). Exosomes are secreted in vivo by almost any cell type and can be isolated from body fluids (4-6). Indeed, circulating vesicles account for both exosomes and microvesicles (MVs), which can be purified by various purification methods and fully discriminated according to their shape, size and CD-markers (7,8). Due to their protein and RNA content, once internalized, exosomes have the potential to act as ˇ°translationalˇ± organelles, altering the expression pattern of recipient cells, their growth, and fate. In fact, exosomes are involved in many of physio-pathological processes, thereby including cancer (9)
%U http://tcr.amegroups.com/article/view/9015/html