%0 Journal Article %T Efficacy and safety of Sijunzi Decoction for chronic fatigue syndrome with spleen deficiency pattern: study protocol for a randomized, double-blind, placebo-controlled trial %A Guang Ji %A Liang Dai %A Miao Wang %A Shi-Gao Zhou %A Wen-Jun Zhou %J SCIE-indexed Journal %D 2019 %R 10.21037/atm.2019.09.136 %X Chronic fatigue syndrome (CFS) is characterized by prolonged and disabling fatigue (>6 months), as well other nonspecific somatic symptoms (1). Epidemiological information of CFS is limited. Available studies reported the prevalence of CFS fluctuated from 0.23% to 2.6% (2-4). Although not life-threatening, CFS would severely impact patients¡¯ quality of life and lead to tremendous social burden (5,6) %U http://atm.amegroups.com/article/view/30395/html