%0 Journal Article %T Very late outcomes of drug-eluting stents coated with biodegradable polymers: insights from the 5-year follow-up of the randomized PAINT trial %A Antonio A.G. Lima %A Bruno Moulin %A Cesar R. Medeiros %A Expedito E. Ribeiro %A Fabio S. Brito Jr %A J. Airton Arruda %A Julio F. Marchini %A Ludmilla A.R.R. Oliveira %A Marco A. Perin %A Mauricio R. Barbosa %A Paulo R.A. Caramori %A Pedro A. Lemos %A Valter C. Lima %A Wilton F. Gomes %J SCIE-indexed Journal %D 2014 %X Drug-eluting stents (DES) are a milestone development in interventional cardiology, due to their ability to reduce the risk of restenosis and repeat revascularization after percutaneous coronary intervention (1). However, in the long run, beyond the so-called ¡°restenosis-period¡°, clinical studies have raised concerns about the very safety of DES (2,3). Delayed stent thrombosis (ST) and neo-atherosclerosis have been reported to occur in patients treated with early DES formulations, potentially related to impaired reendothelialization and hypersensitivity response to polymer carriers (4-7) %U http://cdt.amegroups.com/article/view/5353/6152