%0 Journal Article
%T The effect of time interval on esophagectomy after neoadjuvant treatment
%A Lieven Depypere
%J SCIE-indexed Journal
%D 2016
%R 10.1016/j.athoracsur.2015.09.044
%X The optimal time interval of esophagectomy after neoadjuvant therapy for locally advanced esophageal adenocarcinoma remains largely unknown. Several prospective randomized trials describe a time interval of 3¨C8 weeks between neoadjuvant therapy and esophagectomy (1-3). Extremely prolonged observation after neoadjuvant therapy may lead to salvage esophagectomy which was reported to have a 3-fold increase in perioperative mortality (4). Esophagectomy timing after neoadjuvant therapy has been examined in a few retrospective analyses, with divergent conclusions (5-8)
%U http://atm.amegroups.com/article/view/9071/html