%0 Journal Article %T Safety and efficacy of daily Revactin £¿ in men with erectile dysfunction: a 3-month pilot study %A Jacob Rajfer %A Magda Shaheen %A Sabine Nguyen %J SCIE-indexed Journal %D 2018 %X Erectile dysfunction (ED) is considered an aging related condition such that the older a man gets, the probability of developing some form of ED increases (1). The presumptive functional target tissue within the penis that is primarily affected by the aging process is the corporal smooth muscle cell (CSMC) (2-5) and it is the aging related apoptosis and loss of these CSMC (6,7) that leads to what is termed aging related erectile dysfunction (ARED) (8). Studies in animals have shown that when this aging related apoptotic activity begins within the CSMC, the CSMC itself begins to counteract this apoptotic process by forming nitric oxide (NO) from the inducible nitric oxide synthase (iNOS) enzyme (7) %U http://tau.amegroups.com/article/view/19047/19084