%0 Journal Article %T Prophylactic cranial irradiation in non-small cell lung cancer: the debate is open %A Antonio Rossi %A Carlo Greco %A Sara Ramella %J SCIE-indexed Journal %D 2019 %R 10.21037/jtd.2018.12.119 %X Non-small cell lung cancer (NSCLC) is diagnosed in about 30% of patients as locally advanced disease (stage III) which is defined as a tumour that exceeds the structures of the lung itself, but without clinical evidence of distant spreading. These patients form a highly heterogeneous group with controversial treatment based on the combination of surgery, chemotherapy and radiotherapy (1) %U http://jtd.amegroups.com/article/view/26374/html