%0 Journal Article
%T Clinical application of invasive cardiopulmonary exercise test for dyspnea diagnosis in Chinese people
%A Cheng Hong
%A Chunli Liu
%A Jingping Zheng
%A Nanshan Zhong
%A Nuofu Zhang
%A Shiyue Li
%A Tao Wang
%A Wenli Chen
%A Yanghan Chen
%A Yi Gao
%A Yi Hong
%J SCIE-indexed Journal
%D 2018
%R 10.21037/jtd.2018.10.114
%X Dyspnea is a common clinical manifestation of subjective sensation and objective signs of breathless. There are multiple organic dysfunction or non-organic causes which may lead to dyspnea. In clinical practice, a lot of laboratory and imaging tests are performed to find the etiology of dyspnea, but some patients still remain undiagnosed, which is called unexplained dyspnea (1). Invasive cardiopulmonary exercise test (iCPET) is a new technique developed in recent years, with the addition of right heart and radial artery catheterization combined with traditional cardiopulmonary exercise test (CPET) (2). During the test, right atrium pressure, pulmonary artery pressure, pulmonary capillary wedge pressure and arterial pressure were measured during exercise and at rest (2). Blood from pulmonary artery and radial artery at different time point were sampled for analysis of hemoglobin oxygen saturation and lactic acid. Since a series of hemodynamic and respiratory index were obtained during exercise, iCPET has been introduced for the diagnosis of some types of exertion-induced dyspnea which including exercise-induced left heart diastolic function, exercise-induced pulmonary hypertension, muscle mitochondrial function obstacle, vascular nerve dysfunction. Because of the relatively technical difficulties, iCPET has been performed only in a few medical centers so far. To best of our knowledge, this is the first report of iCPET in China, we will introduce the experience of the first 7 iCPETs in our center (Figure 1). The age of 7 patients receiving iCPET was 27¨C67 years old with 0.5¨C5 years history of dyspnea. All the 7 patients received treatment adjustification based on iCPET results. After 3 months follow-up, 5 patients had improved symptoms (Table 1)
%U http://jtd.amegroups.com/article/view/25281/html