%0 Journal Article %T Efficient cancer gene therapy with a Del1 fragment administered by hypodermic injection in a mouse explanted tumor model %A Chiaki Hidai %A Eri Tamura %A Hisataka Kitano %A Shinichiro Kokubun %A Tomomi Ishikawa %J SCIE-indexed Journal %D 2018 %R 10.21037/21914 %X Numerous technologies have been developed to cure cancer patients. However, surgery, chemotherapy and radiation therapy have limited applications for advanced cancer. Surgery and radiation therapy cannot be repeated many times, and cancer cells develop resistance to chemotherapy in many cases. Additionally, the physical conditions of the patients make some therapeutics unusable. Because of these hurdles, the development of novel therapeutic options is required. One such candidate therapeutic option is biological therapy that exerts its effects by exploiting the biological characteristics of cancer cells and their hosts %U http://tcr.amegroups.com/article/view/21914/html