%0 Journal Article %T The urea cycle enzymes act as metabolic suppressors in clear cell renal cell carcinoma %A Giuseppe Lucarelli %A Matteo Ferro %A Michele Battaglia %A Pasquale Ditonno %J SCIE-indexed Journal %D 2018 %R 10.21037/23259 %X Renal cell carcinoma (RCC) comprises about 3¨C4% of adult malignancies and according to recent estimates, over 65,000 new cases will be diagnosed in 2018 (3.8% of all new cancer cases), and nearly 15,000 patients will die of this tumor (2.5% of all cancer deaths) in the United States (1) %U http://tcr.amegroups.com/article/view/23259/html