%0 Journal Article %T Genetic signatures on prostate biopsy: clinical implications %A Justin T. Matulay %A Sven Wenske %J SCIE-indexed Journal %D 2018 %R 10.21037/20385 %X Prostate cancer is the most common non-cutaneous malignancy in men with 161,000 new diagnoses in 2017 (1). It is a very heterogeneous disease with variable outcomes, depending on disease stage and grade. Due to serum prostate-specific antigen (PSA) screening of men at risk, most patients are diagnosed with indolent disease that does not impact quality of life or life expectancy and is therefore managed expectantly [active surveillance (AS)]. However, some patients will die of their cancer if left untreated %U http://tcr.amegroups.com/article/view/20385/html