%0 Journal Article
%T The Society for Translational Medicine: clinical practice guidelines  for mechanical ventilation management for patients undergoing  lobectomy
%A Alessandro Brunelli
%A Calvin Sze Hang Ng
%A Chang Chen
%A Chia-Chuan Liu
%A Chun Chen
%A Chunfang Zhang
%A Danqing Li
%A Deruo Liu
%A Deyao Xie
%A Erico Ruffini
%A Fenglei Yu
%A Gaetano Rocco
%A Gang Chen
%A Gaofeng Li
%A Gening Jiang
%A Guibin Qiao
%A Haidong Wang
%A Haiquan Chen
%A Haitao Ma
%A Hongjing Jiang
%A Hui Li
%A Jian Hu
%A Jianxing He
%A Jie He
%A Jin-Shing Chen
%A John B. Downs
%A Juwei Mou
%A Lanjun Zhang
%A Lijie Tan
%A Lin Xu
%A Lunxu Liu
%A Mart¨ªnez I. Garutti
%A Qi Xue
%A Qiang Li
%A Qinghua Zhou
%A Qun Wang
%A Qunyou Tan
%A Ren¨¦ H. Petersen
%A Ruwen Wang
%A Shidong Xu
%A Shugeng Gao
%A Shumin Wang
%A Songtao Xu
%A Stephen Cassivi
%A Tang Tong
%A Tao Xue
%A Tao Zhang
%A Tiansheng Yan
%A Weimin Mao
%A Wentao Fang
%A Xiangning Fu
%A Xiaofei Li
%A Xiaojing Zhao
%A Xiuyi Zhi
%A Xuewei Zhao
%A Xun Zhang
%A Yin Li
%A Ying Chai
%A Yongyi Liu
%A Yousheng Mao
%A Yunchao Huang
%A Zhentao Yu
%A Zhijun Li
%A Zhongheng Zhang
%A Zhongmin Jiang
%J SCIE-indexed Journal
%D 2017
%R 10.21037/jtd.2017.08.166
%X Anesthesia for lobectomy in thoracic surgery is a great challenge because it requires single contralateral lung ventilation with collapse of the ipsilateral lung. Collapse of the operated lung and ventilation of the other lung may induce an inflammatory response (1). The ventilated lung is hyperperfused, receiving most of the cardiac output and may be damaged by mechanical ventilation. The collapsed lung is exposed to ischemia, reperfusion injury and shear stress on reexpansion and postresection ventilation. As a result, patients who undergo lobectomy postoperatively may develop compromised lung function. Acute lung injury, reduced lung compliance and hypoxemia and an increase in pro-inflammatory cytokines, all are reported (2-6). The aim of mechanical ventilation during one-lung ventilation is (I) to facilitate carbon dioxide elimination; (II) to maintain oxygenation; and (III) to minimize postoperative lung dysfunction. There have been numerous investigations performed to determine the most appropriate means of mechanical ventilation. In this study we systematically searched the literature and the evidence for each graded recommendation
%U http://jtd.amegroups.com/article/view/15690/html