%0 Journal Article %T Impact of diabetes mellitus on coagulation function before and after off-pump coronary artery bypass grafting %A Dawei Wang %A Fei Yang %A Yu Liu %A Yulei Wei %A Zhenming Zhang %A Ziying Chen %J SCIE-indexed Journal %D 2019 %R 10.21037/jtd.2019.11.27 %X In recent years, off-pump coronary artery bypass grafting (OPCABG) has been widely used in the surgical treatment of coronary heart disease. OPCABG without using a cardiopulmonary artery bypass (CPB) can present the influence of extracorporeal circulation on the human body, may present a number of complications, such as post-procedure myocardial, pulmonary, renal and cerebral complications, and better protect the coagulation mechanism, but may increase the risk of postoperative thrombosis (1-3). It is known that the postoperative graft of vascular stenosis and occlusion eventually leads to serious cardiovascular events, such as myocardial ischemia and myocardial infarction, which result in increased patient mortality. In the early period of post-operation, thrombosis is an important factor that leads to the blockage of grafted vessels, which in turn is closely correlated to thrombosis and coagulation function (1,4). Therefore, the accurate and timely monitoring of coagulation changes in patients, and effective anti-platelet therapy is of significant value to reduce blood vessel thrombosis in the perioperative period %U http://jtd.amegroups.com/article/view/33637/html