%0 Journal Article
%T Younger patients operated for lung cancer have a better prognosis
%A Danush Davoodi
%A Robert Dziedzic
%A Sofie Josefsson
%A Tomasz Marjanski
%A Wioletta Sawicka
%A Witold Rzyman
%J SCIE-indexed Journal
%D 2020
%R 10.21037/jtd.2020.04.55
%X Lung cancer is a leading cause of mortality owing to malignancies in the population of smokers older than 60 years. The median age for primary lung cancer is 70 years old (1) and most papers refer to early lung cancer onset (ELCO) as lung cancer diagnosed before the age of 50 (2). There are conflicting data concerning survival and prognosis in the younger and older lung cancer populations (2-4). Undoubtedly patients with ELCO are a distinct population in comparison with late lung cancer onset (LLCO) patients. There is lower smoking exposure in the ELCO group and the influence of genetic factors has more impact than in LLCO. Carcinoids more commonly occur in the ELCO population compared to more common squamous cell histology in LLCO. Molecular patterns of mutations characterize these groups of patients differently and there are data suggesting a more aggressive course of lung cancer treated at earlier age (3). On the other hand, the younger population is not affected by the number of significant, tobacco-related comorbidities that may influence the overall survival (OS). There are few papers in this field that focus on surgical treatment of early-stage lung cancer solely. The purpose of this study was to compare the differences in survival and prognosis in young and old patients with surgically treated lung cancer
%U http://jtd.amegroups.com/article/view/39013/html