%0 Journal Article
%T Nivolumab induced vitiligo-like lesions in a patient with metastatic squamous cell carcinoma of the lung
%A Fumio Imamura
%A Kazumi Nishino
%A Kei Kunimasa
%A Madoka Kimura
%A Masanori Kitamura
%A Motohiro Tamiya
%A Shin-ichi Nakatsuka
%A Shuichi Ohe
%A Taiki Isei
%A Takako Inoue
%A Toru Kumagai
%J SCIE-indexed Journal
%D 2018
%R 10.21037/jtd.2018.05.104
%X Nivolumab, a fully humanized monoclonal IgG4 antibody blocking programmed cell death-1 (PD-1), has demonstrated improved survival over docetaxel in previously treated patients with advanced non-small cell lung cancer (NSCLC) (1,2). Vitiligo-like depigmentation is a well described immune-related adverse event (irAE) in melanoma patients receiving immunotherapy with PD-1 inhibitors but it¡¯s rare in NSCLC (3). We experienced a rare case of metastatic NSCLC who developed vitiligo-like lesions during nivolumab treatment after excess sunburn. We presented clinical course of this patient with the data of histological and immunohistochemical analysis of the skin lesions
%U http://jtd.amegroups.com/article/view/21552/html