%0 Journal Article
%T Performance evaluation of detecting circulating tumor cells and tumor cells in bronchoalveolar lavage fluid in diagnosis of peripheral lung cancer
%A Chang-Hao Zhong
%A Da Tong
%A Jia Xing
%A Shi-Yue Li
%A Su-Jie Guo
%A Ya-Li Bai
%A Yu-Long Luo
%A Zhu-Quan Su
%A Zi-Qing Zhou
%J SCIE-indexed Journal
%D 2018
%R 10.21037/jtd.2017.12.125
%X Lung cancer is the malignancy with the highest morbidity and mortality in the world. Approximately 18% of cancer deaths are associated with lung cancer (1,2). The 5-year survival rate of lung cancer patients is low which is frequently associated with late diagnosis (3). Therefore, early diagnosis of lung cancer is of clinical importance for improving long-term prognosis. High resolution computed tomography (HRCT), which can display the morphology and location of small peripheral nodes, is the most common technique for early diagnosis of lung cancer. However, a CT examination confers limited value for distinguishing benign lung lesion from malignancy. Although a high magnitude of lung cancer-related tumor marker (e.g., CEA, CA125, and NSE) usually suggest a lung cancer diagnosis, the sensitivity and specificity are not yet high enough for early screening and diagnosis of lung cancer in clinical practice
%U http://jtd.amegroups.com/article/view/18433/html