%0 Journal Article
%T Formulation, Development and Evaluation of Rivaroxaban Tablets by Using Solubility Enhancement Technique
%A Piyush Patel
%J Biocoreopen
%D 2017
%X To enhance solubility and dissolution rate of Rivaroxaban by Inclusion complex with kneading method using Hydroxy propyl £¿2 cyclodextrin. The prepared Rivaroxaban inclusion complex were characterized in term of solubility and dissolution studies, Fourier transform infrared spectroscopy (FTIR). The aqueous solubility and dissolution rate of Rivaroxaban tablets was significantly increased. The dissolution rate of Rivaroxaban tablets was superior with compared to market sample
%K Also found at 1:1 molar ratio found more solubility and no significant different in solubility at higher concentration. From above data Kneading method gives more solubility than physical mixer method. The dissolution profile of formulation of highest solubility (1:1) ratio inclusion complex
%U https://biocoreopen.org/ijpsr/Formulation-development-and-evaluation-of-rivaroxaban-tablets-by-using-solubility-enhancement-technique.php