%0 Journal Article
%T Mutation Profiling of Malignant Lymphoma by Next-Generation Sequencing of Circulating Cell-Free DNA
%A Cui Chen
%A Hang Yang
%A Man Nie
%A Pan-Pan Liu
%A Peng Sun
%A Qiu-Xiang Ou
%A Wen-Qi Jiang
%A Xi-Wen Bi
%A Xue Wu
%A Xue-Wen Zhang
%A Yang W. Shao
%A Yi Xia
%A Yu Wang
%A Zhi-Ming Li
%J Journal of Cancer
%D 2019
%I Ivyspring International Publisher
%R 10.7150/jca.27615
%X Background: Malignant lymphomas are a group of distinct lymphoid neoplasms, exhibiting marked diversity in biological behaviors and clinical outcomes. Liquid biopsy, such as circulating cell-free DNA (cfDNA), has recently been attempted to be used for mutation profiling of lymphomas using next-generation sequencing (NGS). However, only limited data about cfDNA are restricted in Hodgkin's lymphoma and B cell lymphoma, and there is no report in the T cell lymphoma so far.
%K malignant lymphoma
%K circulating cell-free DNA
%K tumor heterogeneity
%K next-generation sequencing (NGS)
%K China
%U http://www.jcancer.org/v10p0323.htm