%0 Journal Article
%T Diagnostic role and limitations of 2-deoxy-2-(F-18) fluoro- D-Glucose positron emission tomography (FDG-PET) in screening of synchronous cancer of other organs in patients with head and neck cancers
%A D. Dequanter
%J International Journal of Otolaryngology | Open Access Journal | Head & Neck Surgery
%D 2017
%X Aim Patients with Head and Neck Squamous Cell Carcinoma (HNSCC) often develop synchronous primary cancers. It is important to detect synchronous cancer in HNSCC patients, because it influences treatment selection of primary cancer. The aim of the study was to evaluate the diagnostic role and limitations of pre-treatment 2-deoxy-2- (F-18) Fluoro-D-Glucose Positron Emission Tomography (FDG-PET) in patients with head and neck cancer. Methods Retrospectively, 181 head and neck cancer patients were reviewed to evaluate the clinical significance of pre-treatment FDG-PET. Results The synchronous primary tumors were lung in ten cases, head and neck in four cases, colon in three cases, bone in three cases, esophagus in two cases, liver in two cases, pancreas in one case, bladder in one case and adrenal gland in one case. The diagnostic sensitivity of FDG-PET for synchronous primary cancers was as follows: esophagus 16,6 % (2/ 12), lung 76,9 % (10/13); head and neck 66,6 % (4/6); bone 75 % (3/4)colon 21,4 % (3/14); bladder 100 % (1/1); thyroid 0% (O/1) and breast 0 % (0/1). Conclusions FDG-PET is an important additional tool for detecting synchronous multiple primary cancers because the diagnostic sensitivity of FDGPET in synchronous head and neck cancer, lung cancer and bone metastasis is high. But the diagnostic sensitivity of FDG-PET to detect esophageal cancer is very low and limited the sensitivity for detection of synchronous multiple primary cancers. Moreover, the rate of incidental colonic foci of 2-deoxy-2- (F-18) fluoro-D-glucose uptake on FDG-PET was very high. Key-words: Synchronous multiple primary cancers; FDG-PET sensitivity; head and neck cance
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