%0 Journal Article
%T Management of acute bacterial sinusitis: a prospective observational, multicenter study focusing on the safety and efficacy of Moxifloxacin
%A Ahmed M
%A Anwar A
%A Baig M
%A Herani I
%A Hussain S
%A Khiyani I
%A Lateef T
%A Maheshwary N
%A Sajjad Q
%A Siddiqi A
%A Zia R
%J International Journal of Otolaryngology | Open Access Journal | Head & Neck Surgery
%D 2017
%X Objective: To observe the efficacy, safety & tolerability of moxifloxacin in patients with Acute Bacterial Sinusitis across Pakistan. Material & Methods: This was the prospective, observational multicenter study in patients diagnosed with Acute Bacterial Sinusitis treated with Moxifloxacin therapy. The convenient sampling technique was used to select the patients. The ethical approval was taken by the institutional research forum of Rawalpindi Medical College. Patient data originating from assessments and evaluations performed according to the physician¡¯s routine practice was collected in a well-designed proforma. SPSS version 20.0 was used to analyze the data. Results: The most common reason for change of medication was failure of the previous therapy in 139 (81%) patients.The comparison of symptoms at 3rd and 14th day period revealed that they were absent in 152 (88.4%) patients at 14th day, while mild and severs symptoms were reduced to 17(9.9%) and 3(1.7%) patients with a significant p value of 0.004. The most common adverse effect was dizziness that was found in 30% of the cases followed by nausea and vomiting, others like palpitation, body ache and gastric upsets and dry mouth in 7%, 6% and 4% cases respectively. Conclusion: Moxifloxacin is effective in resolving the symptoms of acute bacterial sinusitis. It is more effective than other antibiotics because of its efficacy and least side effects. The medicating of simple once daily dosage offer benefits over many existing agents in terms of compliance as well. Keywords: Management of Acute Bacterial Sinusitis; Safety and Efficacy of Moxifloxacin
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