%0 Journal Article
%T An end in sight? Xrn2 and transcriptional termination by RNA polymerase II
%A Joshua D. Eaton
%A Steven West
%J Archive of "Transcription".
%D 2018
%R 10.1080/21541264.2018.1498708
%X Every transcription cycle ends in termination when RNA polymerase dissociates from the DNA. Although conceptually simple, the mechanism has proven somewhat elusive in eukaryotic systems. Gene-editing and high resolution polymerase mapping now offer clarification of important steps preceding transcriptional termination by RNA polymerase II in human cells
%K Xrn2
%K RNA polymerase II (Pol II)
%K transcriptional termination
%K 3กฏ end processing
%K cleavage and polyadenylation
%K RNA degradation
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150625/