%0 Journal Article %T Alpha-synuclein overexpression in the olfactory bulb initiates prodromal symptoms and pathology of Parkinson¡¯s disease %A Chao Ren %A Deqin Geng %A Haichen Niu %A Haiying Li %A Lei Wang %A Lingyu Shen %A Qiang Zhang %A Sheng Ding %A Tongzhou Li %A Xiaoyu Liu %A Xiujuan Wu %A Zhonghai Zhang %J Archive of "Translational Neurodegeneration". %D 2018 %R 10.1186/s40035-018-0128-6 %X Identification of AAV hm-¦Á-Syn expression in the OB. a Nissl stained section showing an example of the OB injection. Arrows point to the precise location of the site of the needle tract. b Representative examples of the GFP labeling patterns from the AAV-hm-¦Á-Syn-GFP and control AAV-GFP injection animals. c Comparison of the numbers of GFP positive cells between the AAV-hm-¦Á-Syn-GFP and control AAV-GFP injected animal %K Alpha-synuclein %K Prodromal animal model %K Parkinson¡¯s disease %K Olfactory bulb %K Autophagy %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192070/