%0 Journal Article %T World Allergy Organization-McMaster University Guidelines for Allergic Disease Prevention (GLAD-P): Prebiotics %A Alessandro Fiocchi %A Andrea Vereda %A Arnav Agarwal %A Bee Wah Lee %A Carlos A. Cuello-Garcia %A Gian Paolo Morgano %A Giorgio W. Canonica %A Haiqi Li %A Holger J. Sch¨¹nemann %A Hugh Sampson %A Jan L. Bro£¿ek %A John J. Riva %A Juan Jos¨¦ Yepes-Nu£¿ez %A Kangmo Ahn %A Kirsten Beyer %A Lanny Rosenwasser %A Luigi Terracciano %A Michael Spigler %A Motohiro Ebisawa %A Rose Kamenwa %A Ruby Pawankar %A Shreyas Gandhi %A Suleiman Al-Hammadi %A Susan Prescott %A Susan Waserman %A Wesley Burks %A Yuan Zhang %J Archive of "The World Allergy Organization Journal". %D 2016 %R 10.1186/s40413-016-0102-7 %X The prevalence of allergic diseases in infants, whose parents and siblings do not have allergy, is approximately 10 % and reaches 20¨C30 % in those with an allergic first-degree relative. Intestinal microbiota may modulate immunologic and inflammatory systemic responses and, thus, influence development of sensitization and allergy. Prebiotics ¨C non-digestible oligosaccharides that stimulate growth of probiotic bacteria ¨C have been reported to modulate immune responses and their supplementation has been proposed as a preventive intervention %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772464/