%0 Journal Article
%T Synergistic inhibition of MEK/ERK and BRAF V600E with PD98059 and PLX4032 induces sodium/iodide symporter (NIS) expression and radioiodine uptake in BRAF mutated papillary thyroid cancer cells
%A Dong Chen
%A Honglai Zhang
%J Archive of "Thyroid Research".
%D 2018
%R 10.1186/s13044-018-0057-6
%X Western blot of NIS in lysates of BCPAP cells (a) and K1 cells (b) treated with PLX4032 (0.001¨C0.1 ¦ÌM) or PD98059 (0.001¨C0.1 ¦ÌM) or their combination for indicated time
%K Papillary thyroid carcinoma
%K Assodium/iodide symporter
%K Mutation BRAFV600E
%K Mitogen-activated protein kinase
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180498/