%0 Journal Article
%T A Proteome Reference Map of the Causative Agent of Melioidosis Burkholderia pseudomallei
%A Patompon Wongtrakoongate
%A Sittiruk Roytrakul
%A Sukkid Yasothornsrikul
%A Sumalee Tungpradabkul
%J Journal of Biomedicine and Biotechnology
%D 2011
%I Hindawi Publishing Corporation
%R 10.1155/2011/530926
%X Burkholderia pseudomallei is the etiologic agent of melioidosis. Using 2DE and MALDI-TOF MS, we report here a proteome reference map constructed from early stationary phase, a bacterial adaptation process. We identified 282 protein spots representing 220 ORFs; many of them have been implicated in bacterial pathogenesis. Up to 20% of identified ORFs belong to post-translational modification and stress responses. The proteome reference map will support future analysis of the bacterial gene and environmental regulation and facilitate comparative proteomics with its sibling species.
%U http://www.hindawi.com/journals/biomed/2011/530926/