%0 Journal Article
%T Reply
%A Allen P. Kaplan
%A Anete S. Grumach
%A Anna Feldweg
%A Chiara Suffritti
%A Dana Vuzman
%A Henriette Farkas
%A Konrad Bork
%A Kusumam Joseph
%A Lakiea Wright
%A Lilian Varga
%A Marco Cicardi
%A Natasha Frank
%A Rohit Sharma
%A Rosemeire N. Constantino-Silva
%J Journal of Allergy and Clinical Immunology
%D 2017
%R 10.1016/j.jaci.2016.12.983
%X The comments by Marlu et£¿al1 regarding our article on plasminogen activator inhibitor
2 (PAI-2) deficiency in patients with hereditary angioedema with normal C1 inhibitor
(HAE-N) is timely and interesting. The very low levels observed in 22 of 23 untreated
patients with HAE-N (with or without a factor XII mutation, 4.5£¿¡À£¿5) were similar
to the levels in 11 patients reported in their commentary, but the PAI-2 mean values
in normal controls (54£¿¡À£¿24) and patients with HAE type I (84£¿¡À£¿52) were over 10 times
higher.
%U https://www.jacionline.org/article/S0091-6749(17)30234-8/abstract