%0 Journal Article
%T Parental Allergic Diseases Associate with Skin Hypersensitivity to Histamine in Their Infants
%A Kenji Matsumoto
%A Miwa Shinohara
%J Journal of Allergy and Clinical Immunology
%D 2017
%R 10.1016/j.jaci.2016.12.468
%X Histamine regulates immune response and inflammation, and impairs the skin barrier
dysfunction that initiates a clinical manifestation of eczema, and then atopic dermatitis
(AD). Using skin prick tests (SPTs) to histamine as a marker of skin hypersensitivity
mediated mast cells, we investigated whether parental allergic diseases affect skin
hypersensitivity to histamine and skin diseases in their infants.
%U https://www.jacionline.org/article/S0091-6749(16)31986-8/abstract