%0 Journal Article
%T Human Hemopoietic Progenitor Cell Toll-like and Thymic Stromal Lymphopoietin Receptor Expression and Function in Allergic Asthmatic Subjects
%A Damian Tworek
%A Delia Heroux
%A Judah A. Denburg
%A Paul M. O'Byrne
%A Seamus N. O'Byrne
%J Journal of Allergy and Clinical Immunology
%D 2016
%R 10.1016/j.jaci.2015.12.247
%X We demonstrated that cord blood human progenitor cells (HPC) from high allergic risk
newborns expressed Toll-like receptors (TLR) less abundantly than low allergic risk
infants. We also have recently found a key role for thymic stromal lymphopoietin (TSLP)
in human eosinophil and basophil differentiation from HPC in allergic subjects. However,
TLR or TLR-induced TSLP receptor (TSLPR) expression by HPC has never been studied
in allergic asthmatic subjects.
%U https://www.jacionline.org/article/S0091-6749(15)01989-2/abstract