%0 Journal Article
%T Allergen Exposure Increases Triggering Receptor Expressed on Myeloid Cell (TREM)-2 Expression on Lung Dendritic Cell Subsets in a Murine Model of Asthma
%A Devendra K. Agrawal
%A Sannette C. Hall
%J Journal of Allergy and Clinical Immunology
%D 2016
%R 10.1016/j.jaci.2015.12.076
%X Dendritic cells (DCs) are professional antigen presenting cells which traffic from
the lungs to the lymph nodes to present processed antigens to T-cells driving an inflammatory
(Th2) response in atopic individuals. The recently discovered TREM-2 surface receptor
has been shown to be expressed on dendritic cells; however, its role in asthma is
yet to be elucidated. Here, we examined the effect of allergen exposure on TREM-2
expression in the airways and on lung DC subsets.
%U https://www.jacionline.org/article/S0091-6749(15)01818-7/abstract