%0 Journal Article
%T EPIT decreases T1D incidence in sensitized non obese diabetic mice: a likely bystander effect of EPIT-induced Tregs
%A Benjamin Pelletier
%A Christophe M. Dupont
%A Hugh A. Sampson
%A Lucie Mondoulet
%A Melanie Ligouis
%A Pierre-Henri Benhamou
%A Veronique Dhelft
%J Journal of Allergy and Clinical Immunology
%D 2017
%R 10.1016/j.jaci.2016.12.007
%X Epicutaneous immunotherapy (EPIT) has the potency to generate significantly Foxp3+CD62L+
Tregs in mice. In previous published works, we have shown that EPIT-induced Tregs
prevent from further sensitizations in sensitized mice. The aim of this study was
to highlight the potency of this bystander effect conferred by EPIT-induced Tregs
on the treatment of autoimmune disorders such as Type 1 Diabetes (T1D).
%U https://www.jacionline.org/article/S0091-6749(16)31525-1/abstract