%0 Journal Article
%T Intracellular Expression of Fluorochrome Labelled-Diamine Oxidase in Basophils: A Novel Diagnostic Tool for Peanut Allergy
%A Abigail O. Robb
%A Andrew Clark
%A Mohamed H. Shamji
%A Paul J. Turner
%A Robert J. Boyle
%A Stephen R. Durham
%A Yasmin R. Mohseni
%J Journal of Allergy and Clinical Immunology
%D 2016
%R 10.1016/j.jaci.2015.12.583
%X Peanut allergy is a leading cause of fatal anaphylaxis. Labelled intracellular Diamine
Oxidase (DAO) has been used to measure basophil histamine release at a single cell
level. We hypothesized that the intracellular DAO assay can be used a functional diagnostic
tool for identifying peanut allergic patients, and monitor basophil response following
an oral peanut challenge, which may improve our ability to predict those at risk of
anaphylaxis.
%U https://www.jacionline.org/article/S0091-6749(15)02325-8/abstract