%0 Journal Article %T Clinical Factors Associated with Acute Exacerbations of Chronic Rhinosinusitis %A Amy Yang %A Anju T. Peters %A Bruce K. Tan %A David B. Conley %A Jason Kwah %A Kevin C. Welch %A Leslie C. Grammer %A Robert C. Kern %A Robert P. Schleimer %A Stephanie S. Smith %A Whitney W. Stevens %J Journal of Allergy and Clinical Immunology %D 2017 %R 10.1016/j.jaci.2016.12.259 %X Chronic rhinosinusitis (CRS) can be complicated by frequent acute exacerbations leading to significant morbidity and healthcare burden. Our objective was to identify clinical factors associated with frequent acute exacerbations in patients with CRS. %U https://www.jacionline.org/article/S0091-6749(16)31777-8/abstract