%0 Journal Article %T Reply %A Anne M. Fitzpatrick %A Daniel J. Jackson %A David Mauger %A Stanley J. Szefler %J Journal of Allergy and Clinical Immunology %D 2017 %R 10.1016/j.jaci.2017.06.018 %X Longo et£¿al1 raise an interesting issue regarding the differentiation of eosinophilic asthma that may be nonatopic in nature. As indicated in our study, the likelihood of a favorable response to daily inhaled corticosteroid therapy in young children with emerging asthma was associated with either a blood eosinophil count of greater than or equal to 300£¿cells/mm3 or allergic sensitization as defined by multiallergen testing.2 The combination of these 2 features enhanced the likelihood of a favorable response as compared with our other 2 treatment strategies, either daily oral montelukast or inhaled corticosteroid administered with albuterol at the time of symptoms. %U https://www.jacionline.org/article/S0091-6749(17)31096-5/abstract