%0 Journal Article
%T Cholestenoic acid is a prognostic biomarker in acute respiratory distress syndrome
%A Anne E. Dixon
%A Benjamin T. Suratt
%A Eric D. Morrell
%A Fred B. Lih
%A Jennifer H. Madenspacher
%A Julie M. Lowe
%A Kara J. Mould
%A Kenneth B. Tomer
%A Mark M. Wurfel
%A Michael B. Fessler
%A Renee D. Stapleton
%A Stavros Garantziotis
%A William J. Janssen
%J Journal of Allergy and Clinical Immunology
%D 2019
%R 10.1016/j.jaci.2018.09.017
%X Despite improvements in supportive care, mortality from acute respiratory distress
syndrome (ARDS) remains high (approximately 30% to 40%).1 In recent years, several
biomarkers of inflammation, epithelial damage, endothelial damage, and coagulation
have been identified that show promise for identifying ARDS endotypes with different
prognosis and therapeutic responsiveness.1 Unfortunately, few lung-specific biomarkers
have been validated, and none have been adopted into routine clinical practice.
%U https://www.jacionline.org/article/S0091-6749(18)31368-X/abstract