%0 Journal Article
%T Bcl2-like protein 12 plays a critical role in development of airway allergy through inducing aberrant TH2 polarization
%A Guang-Ji Zhang
%A Jiang-Qi Liu
%A Li-Hua Mo
%A Ping-Chang Yang
%A Rui-Di Xie
%A Shan-Dong Wu
%A Xian-Hai Zeng
%A Ying Feng
%A Zhi-Gang Liu
%A Zhi-Qiang Liu
%J Journal of Allergy and Clinical Immunology
%D 2019
%R 10.1016/j.jaci.2018.07.045
%X Although it is well understood that skewed TH2 polarization plays a critical role
in the pathogenesis of allergic asthma,1 the mechanism of TH2 polarization remains
elusive.2 Our recent studies showed that Bcl2-like protein 12 (Bcl2L12) was associated
with pathogenesis of TH2-biased inflammation in the intestine by facilitating TH2
polarization.3 Thus we hypothesize that Bcl2L12 might be also associated with the
pathogenesis of allergic asthma.
%U https://www.jacionline.org/article/S0091-6749(18)31293-4/abstract