%0 Journal Article
%T Basophils and IL-4 Dampen the Protective Innate Immune Response Against Cutaneous Staphylococcus aureus Infection
%A Raif S. Geha
%A null
%J Journal of Allergy and Clinical Immunology
%D 2018
%R 10.1016/j.jaci.2017.12.056
%X Staphylococcus aureus (S. aureus) is responsible for the majority of bacterial skin
and soft tissue infections. Furthermore, S. aureus is commonly present in patients
with atopic dermatitis, a disease characterized by scratching, which inflicts mechanical
injury to the skin. It is currently not fully understood how S. aureus evades the
protective immune response mounted by the host. We investigated the regulation of
skin innate immune response to S. aureus infection of mechanically injured skin.
%U https://www.jacionline.org/article/S0091-6749(17)31956-5/abstract