%0 Journal Article
%T Cryj 1, a major allergen of Japanese cedar pollen, up-regulates the effector functions of eosinophils
%A Hidetomo Nakamoto
%A Kazuyuki Nakagome
%A Kouhei Saitou
%A Makoto Nagata
%A Sachiko Miyauchi
%A Takehito Kobayashi
%A Tomoyuki Soma
%A Toru Noguchi
%J Journal of Allergy and Clinical Immunology
%D 2018
%R 10.1016/j.jaci.2017.12.228
%X Japanese cedar pollinosis is the most common form of pollinosis in Japan and has recently
remarkably increased. There is evidence that eosinophils play important roles in the
development of aggravating the clinical symptoms of the allergic rhinitis or bronchial
asthma. In this study, we examined whether Cryj 1, which is the major Japanese cedar
pollen allergen, could directly modifies eosinophil functions such as superoxide anion
(O2£¿) generation and adhesion.
%U https://www.jacionline.org/article/S0091-6749(17)32128-0/abstract