%0 Journal Article
%T Airway IL-1¦Á promotes development of allergen-specific follicular helper T (Tfh) cells and production of IgE antibody
%A Koji Iijima
%A Takao Kobayashi
%A Takayasu Nomura
%A null
%J Journal of Allergy and Clinical Immunology
%D 2018
%R 10.1016/j.jaci.2017.12.254
%X Recent literature suggests that Tfh cells that produce IL-4 play a pivotal role in
allergic immune responses. However, the molecular and immunological mechanisms involved
in the development of Tfh cells are not fully understood. The goal of this study was
to test the hypothesis that IL-1¦Á released from alveolar macrophage plays a pivotal
role in respiratory allergy.
%U https://www.jacionline.org/article/S0091-6749(17)32154-1/abstract