%0 Journal Article
%T Noncoding RNA Expression and Targeted Next-Generation Sequencing Distinguish Tubulocystic Renal Cell Carcinoma (TC-RCC) from Other Renal Neoplasms
%A Angela M. Araujo
%A Carla Sole
%A Charles H. Lawrie
%A Erika Larrea
%A Ibai Goicoechea
%A Isabel Alvarado-Cabrero
%A Jos¨¦ I. L¨®pez
%A Lorea Manterola
%A Maris Sperga
%A Marta Fernandez-Mercado
%A Mar¨ªa Arest¨ªn
%A Mar¨ªa Armesto
%A Mar¨ªa M. Caffarel
%A Michal Michal
%A Ondrej Hes
%J The Journal of Molecular Diagnostics
%D 2018
%R 10.1016/j.jmoldx.2017.09.002
%X Tubulocystic renal cell carcinoma (TC-RCC) is a rare recently described renal neoplasm
characterized by gross, microscopic, and immunohistochemical differences from other
renal tumor types and was recently classified as a distinct entity. However, this
distinction remains controversial particularly because some genetic studies suggest
a close relationship with papillary RCC (PRCC). The molecular basis of this disease
remains largely unexplored. We therefore performed noncoding (nc) RNA/miRNA expression
analysis and targeted next-generation sequencing mutational profiling on 13 TC-RCC
cases (11 pure, two mixed TC-RCC/PRCC) and compared with other renal neoplasms.
%U https://jmd.amjpathol.org/article/S1525-1578(17)30201-5/fulltext