%0 Journal Article
%T The Application of Molecular Diagnostics to Stained Cytology Smears
%A Andrew Seymour
%A Antonio Cajigas
%A Eli Grunblatt
%A Esther Adler
%A Evan Pieri
%A Laleh Hakima
%A Maja H. Oktay
%A Mark Suhrland
%A Samer Khader
%A Sumanta Goswami
%J The Journal of Molecular Diagnostics
%D 2016
%R 10.1016/j.jmoldx.2016.01.007
%X Detection of mutational alterations is important for guiding treatment decisions of
lung non¨Csmall-cell carcinomas and thyroid nodules with atypical cytologic findings.
Inoperable lung tumors requiring further testing for staging and thyroid lesions often
are diagnosed using only cytology material. Molecular diagnostic tests of these samples
typically are performed on cell blocks; however, insufficient cellularity of cell
blocks is a limitation for test performance. In addition, some of the fixatives used
while preparing cell blocks often introduces artifacts for mutation detection.
%U https://jmd.amjpathol.org/article/S1525-1578(16)00052-0/fulltext