%0 Journal Article
%T Spectroscopic Photoacoustic Molecular Imaging of Breast Cancer using a B7-H3-targeted ICG Contrast Agent
%A Jščrgen K. Willmann
%A Katheryne E. Wilson
%A Kristen Jensen
%A Lotfi Abou-Elkacem
%A Lu Tian
%A Steven Machtaler
%A Sunitha V. Bachawal
%J Theranostics
%D 2017
%I Ivyspring International Publisher
%R 10.7150/thno.18217
%X Purpose: Breast cancer imaging methods lack diagnostic accuracy, in particular for patients with dense breast tissue, and improved techniques are critically needed. The purpose of this study was to evaluate antibody-indocyanine green (ICG) conjugates, which undergo dynamic absorption spectrum shifts after cellular endocytosis and degradation, and spectroscopic photoacoustic (sPA) imaging to differentiate normal breast tissue from breast cancer by imaging B7-H3, a novel breast cancer associated molecular target.
%K Photoacoustic Imaging
%K Breast Cancer
%K Molecular Imaging
%K Spectroscopic
%K Indocyanine Green
%U http://www.thno.org/v07p1463.htm